Detection of CYP2C19 Genetic Variants in Malaysian Orang Asli from Massively Parallel Sequencing Data.

Detection of CYP2C19 Genetic Variants in Malaysian Orang Asli from Massively Parallel Sequencing Data.

The human cytochrome P450 (CYP) is a superfamily of enzymes that have been a focus in research for decades due to their prominent role in drug metabolism. CYP2C is one of the major subfamilies which metabolize more than 10% of all clinically used drugs. In the context of CYP2C19, several key genetic...

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Bibliographic Details
Main Authors: Geik Yong Ang, Choo Yee Yu, Vinothini Subramaniam, Mohd Ikhmal Hanif Abdul Khalid, Tuan Azlin Tuan Abdu Aziz, Richard Johari James, Aminuddin Ahmad, Thuhairah Abdul Rahman, Fadzilah Mohd Nor, Adzrool Idzwan Ismail, Kamarudzaman Md Isa, Hood Salleh, Lay Kek Teh, Mohd Zaki Salleh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5087908?pdf=render

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http://europepmc.org/articles/PMC5087908?pdf=render

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