High-Resolution RNA Maps Suggest Common Principles of Splicing and Polyadenylation Regulation by TDP-43

High-Resolution RNA Maps Suggest Common Principles of Splicing and Polyadenylation Regulation by TDP-43

Summary: Many RNA-binding proteins (RBPs) regulate both alternative exons and poly(A) site selection. To understand their regulatory principles, we developed expressRNA, a web platform encompassing computational tools for integration of iCLIP and RNA motif analyses with RNA-seq and 3′ mRNA sequencin...

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Bibliographic Details
Main Authors: Gregor Rot, Zhen Wang, Ina Huppertz, Miha Modic, Tina Lenče, Martina Hallegger, Nejc Haberman, Tomaž Curk, Christian von Mering, Jernej Ule
Format: Article
Language:English
Published: Elsevier 2017-05-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717305223

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http://www.sciencedirect.com/science/article/pii/S2211124717305223

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