Eukaryotic TLS polymerases

TLS polymerases are able to replicate damaged DNA (called translesion DNA synthesis, TLS). Their presence prevents cell death as a result of violating the integrity of the genome. In vitro, they are mutator, but in vivo are recruited by specific types of DNA damage and usually replicate them in a co...

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Bibliographic Details
Main Authors: Przemysław Tomczyk, Ewelina Synowiec, Daniel Wysokiński, Katarzyna Woźniak
Format: Article
Language:English
Published: Index Copernicus International S.A. 2016-05-01
Series:Postępy Higieny i Medycyny Doświadczalnej
Subjects:
Online Access:http://phmd.pl/gicid/01.3001.0009.6832