Central Administration of Lipopolysaccharide Induces Depressive-like Behavior <it>in Vivo </it>and Activates Brain Indoleamine 2,3 Dioxygenase In Murine Organotypic Hippocampal Slice Cultures

Central Administration of Lipopolysaccharide Induces Depressive-like Behavior <it>in Vivo </it>and Activates Brain Indoleamine 2,3 Dioxygenase In Murine Organotypic Hippocampal Slice Cultures

<p>Abstract</p> <p>Background</p> <p>Transient stimulation of the innate immune system by an intraperitoneal injection of lipopolysaccharide (LPS) activates peripheral and central expression of the tryptophan degrading enzyme indoleamine 2,3 dioxygenase (IDO) which medi...

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Bibliographic Details
Main Authors: Kavelaars Annemieke, O'Connor Jason C, Zunich Samantha M, Fu Xin, Dantzer Robert, Kelley Keith W
Format: Article
Language:English
Published: BMC 2010-08-01
Series:Journal of Neuroinflammation
Online Access:http://www.jneuroinflammation.com/content/7/1/43

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http://www.jneuroinflammation.com/content/7/1/43

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