Allele and genotype frequencies of the two single nucleotide polymorphisms in the VKORC1 gene that are most important for warfarin treatment among Emiratis

Allele and genotype frequencies of the two single nucleotide polymorphisms in the VKORC1 gene that are most important for warfarin treatment among Emiratis

Warfarin is the most widely prescribed anticoagulant worldwide. However, warfarin doses vary up to 20-fold and side-effects (at high doses) or therapy failure (at lower doses) are major risks of treatment. The target enzyme of warfarin, vitamin K epoxide reductase complex 1 (VKORC1), is encoded by t...

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Bibliographic Details
Main Authors: Hayat S Al-Jaibeji, Anne John, Lihadh Al-Gazali, Karem Soliman, Abderrahim Oulhaj, Theodora Katsila, Angela Brand, George P Patrinos, Bassam R Ali
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2016-01-01
Series:Hamdan Medical Journal
Online Access:http://www.hamdanjournal.org/article.asp?issn=2227-2437;year=2016;volume=9;issue=1;spage=75;epage=84;aulast=Al-Jaibeji;type=0

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http://www.hamdanjournal.org/article.asp?issn=2227-2437;year=2016;volume=9;issue=1;spage=75;epage=84;aulast=Al-Jaibeji;type=0

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