CCL21/CCR7 prevents apoptosis via the ERK pathway in human non-small cell lung cancer cells.

Previously, we confirmed that C-C chemokine receptor 7 (CCR7) promotes cell proliferation via the extracellular signal-regulated kinase (ERK) pathway, but its role in apoptosis of non-small cell lung cancer (NSCLC) cell lines remains unknown. A549 and H460 cells of NSCLC were used to examine the eff...

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Bibliographic Details
Main Authors: Ying Xu, Lifeng Liu, Xueshan Qiu, Zihui Liu, Haiying Li, Zixuan Li, Wenting Luo, Enhua Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3306387?pdf=render