Development of an LDL Receptor-Targeted Peptide Susceptible to Facilitate the Brain Access of Diagnostic or Therapeutic Agents

Development of an LDL Receptor-Targeted Peptide Susceptible to Facilitate the Brain Access of Diagnostic or Therapeutic Agents

Blood-brain barrier (BBB) crossing and brain penetration are really challenging for the delivery of therapeutic agents and imaging probes. The development of new crossing strategies is needed, and a wide range of approaches (invasive or not) have been proposed so far. The receptor-mediated transcyto...

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Bibliographic Details
Main Authors: Séverine André, Lionel Larbanoix, Sébastien Verteneuil, Dimitri Stanicki, Denis Nonclercq, Luce Vander Elst, Sophie Laurent, Robert N. Muller, Carmen Burtea
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Biology
Subjects:
LDL receptor
brain delivery
peptides
phage display
ultrasmall superparamagnetic particles of iron oxide
CF770
Online Access:https://www.mdpi.com/2079-7737/9/7/161

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https://www.mdpi.com/2079-7737/9/7/161

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