Wilms' tumor gene 1 (WT1) silencing inhibits proliferation of malignant peripheral nerve sheath tumor sNF96.2 cell line.

Wilms' tumor gene 1 (WT1) plays complex roles in tumorigenesis, acting as tumor suppressor gene or an oncogene depending on the cellular context. WT1 expression has been variably reported in both benign and malignant peripheral nerve sheath tumors (MPNSTs) by means of immunohistochemistry. The...

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Bibliographic Details
Main Authors: Rosalba Parenti, Venera Cardile, Adriana Carol Eleonora Graziano, Carmela Parenti, Assunta Venuti, Maria Paola Bertuccio, Debora Lo Furno, Gaetano Magro
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4256418?pdf=render