Assessment of brain beta-amyloid deposition in transgenic mouse models of Alzheimer’s disease with PET imaging agents 18F-flutemetamol and 18F-florbetaben

Assessment of brain beta-amyloid deposition in transgenic mouse models of Alzheimer’s disease with PET imaging agents 18F-flutemetamol and 18F-florbetaben

Abstract Background Although amyloid beta (Aβ) imaging is widely used for diagnosing and monitoring Alzheimer’s disease in clinical fields, paralleling comparison between 18F-flutemetamol and 18F-florbetaben was rarely attempted in AD mouse model. We performed a comparison of Aβ PET images between 1...

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Bibliographic Details
Main Authors: Hye Joo Son, Young Jin Jeong, Hyun Jin Yoon, Sang Yoon Lee, Go-Eun Choi, Ji-Ae Park, Min Hwan Kim, Kyo Chul Lee, Yong Jin Lee, Mun Ki Kim, Kook Cho, Do-Young Kang
Format: Article
Language:English
Published: BMC 2018-07-01
Series:BMC Neuroscience
Subjects:
PET/CT imaging
Alzheimer’s disease
transgenic mouse model
18F-flutemetamol
18F-florbetaben
Online Access:http://link.springer.com/article/10.1186/s12868-018-0447-7

Internet

http://link.springer.com/article/10.1186/s12868-018-0447-7

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