Optimization and validation of an RP-HPLC method for the estimation of 6-mercaptopurine in bulk and pharmaceutical formulations
A reverse phase HPLC method is described for the determination of 6-mercaptopurine in bulk and tablets. Chromatography was carried on a C18 column using a mixture of acetonitrile and 0.05 mol/L sodium acetate buffer (10:90 v/v) as the mobile phase at a flow rate of 1 mL/min-1 with detection at 324 n...
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Format: | Article |
Language: | English |
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Universidade de São Paulo
2014-12-01
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Series: | Brazilian Journal of Pharmaceutical Sciences |
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Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502014000400793&lng=en&tlng=en |