Hypoxia-Induced Adaptations of miRNomes and Proteomes in Melanoma Cells and Their Secreted Extracellular Vesicles

Hypoxia-Induced Adaptations of miRNomes and Proteomes in Melanoma Cells and Their Secreted Extracellular Vesicles

Reduced levels of intratumoural oxygen are associated with hypoxia-induced pro-oncogenic events such as invasion, metabolic reprogramming, epithelial−mesenchymal transition, metastasis and resistance to therapy, all favouring cancer progression. Small extracellular vesicles (EV) shuttle va...

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Bibliographic Details
Main Authors: Geoffroy Walbrecq, Odile Lecha, Anthoula Gaigneaux, Miriam R. Fougeras, Demetra Philippidou, Christiane Margue, Milène Tetsi Nomigni, François Bernardin, Gunnar Dittmar, Iris Behrmann, Stephanie Kreis
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Cancers
Subjects:
melanoma
hypoxia
extracellular vesicles
proteome
mirnome
Online Access:https://www.mdpi.com/2072-6694/12/3/692

Internet

https://www.mdpi.com/2072-6694/12/3/692

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