Time Clustered Sampling Can Inflate the Inferred Substitution Rate in Foot-And-Mouth Disease Virus Analyses.

With the emergence of analytical software for the inference of viral evolution, a number of studies have focused on estimating important parameters such as the substitution rate and the time to the most recent common ancestor (tMRCA) for rapidly evolving viruses. Coupled with an increasing abundance...

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Bibliographic Details
Main Authors: Casper-Emil T Pedersen, Peter Frandsen, Sabenzia N Wekesa, Rasmus Heller, Abraham K Sangula, Jemma Wadsworth, Nick J Knowles, Vincent B Muwanika, Hans R Siegismund
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4667911?pdf=render