Characterizing the Retinoblastoma 1 Locus: a plethora of putative elements for Rb1 regulation by in silico analysis

Characterizing the Retinoblastoma 1 Locus: a plethora of putative elements for Rb1 regulation by in silico analysis

Limited understanding of the Rb1 locus hinders genetic and epigenetic analyses of Retinoblastoma, a childhood cancer of the nervous systems. In this study, we used in silico tools to investigate and review putative genetic and epigenetic elements of the Rb1 gene. We report transcription start sites,...

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Bibliographic Details
Main Authors: Mohammadreza eHajjari, Atefeh eKhoshnevisan, Bernardo eLemos
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-01-01
Series:Frontiers in Genetics
Subjects:
CpG Islands
Retinoblastoma
epigenetics
Rb1
in silico analysis
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00002/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00002/full

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