Oxysterol efflux from macrophage foam cells: the essential role of acceptor phospholipid

Oxidized forms of cholesterol (oxysterols) are present in atherosclerotic lesions and may play an active role in lesion development. For example, 7-ketocholesterol (7KC) inhibits cholesterol efflux from macrophage foam cells induced by apolipoprotein A-I (apoA-I). Such oxysterols may promote foam ce...

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Bibliographic Details
Main Authors: Ingrid C. Gelissen, Kerry-Ann Rye, Andrew J. Brown, Roger T. Dean, Wendy Jessup
Format: Article
Language:English
Published: Elsevier 1999-09-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752033409X