Lipid accelerating the fibril of islet amyloid polypeptide aggravated the pancreatic islet injury in vitro and in vivo

Lipid accelerating the fibril of islet amyloid polypeptide aggravated the pancreatic islet injury in vitro and in vivo

Abstract Background The fibrillation of islet amyloid polypeptide (IAPP) triggered the amyloid deposition, then enhanced the loss of the pancreatic islet mass. However, it is not clear what factor is the determinant in development of the fibril formation. The aim of this study is to investigate the...

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Bibliographic Details
Main Authors: Xiao-Dan Mo, Li-Ping Gao, Qing-Jun Wang, Jie Yin, Yu-Hong Jing
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Lipids in Health and Disease
Subjects:
IAPP
Lipid
Pancreatic islet
T2DM
Insulin
Palmitate
Online Access:http://link.springer.com/article/10.1186/s12944-018-0694-8

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http://link.springer.com/article/10.1186/s12944-018-0694-8

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