Pregnane Xenobiotic Receptors and Their Effect on Drug Elimination from the Organism

Nuclear receptors are intracellular proteins which, having been activated by their more or less specific ligands, regulate (usually increase) the transcription of target genes. They thus participate in a regulation of a number of physiologic functions. Some of them – especially pregnane xenobiotic r...

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Bibliographic Details
Main Authors: Martin Šíma, I. Netíková, O. Slanař
Format: Article
Language:English
Published: Karolinum Press 2013-01-01
Series:Prague Medical Report
Subjects:
Online Access:https://pmr.lf1.cuni.cz/114/4/0205/