Selective Disruption of the Blood–Brain Barrier by Zika Virus

Selective Disruption of the Blood–Brain Barrier by Zika Virus

The blood–brain barrier (BBB) selectively regulates the cellular exchange of macromolecules between the circulation and the central nervous system (CNS). Here, we hypothesize that Zika virus (ZIKV) infects the brain via a disrupted BBB and altered expression of tight junction (TJ) proteins, which ar...

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Bibliographic Details
Main Authors: Ana Rachel Leda, Luc Bertrand, Ibolya Edit Andras, Nazira El-Hage, Madhavan Nair, Michal Toborek
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Microbiology
Subjects:
Zika virus
blood–brain barrier
endothelial cells
tight junctions
neuroinfection
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.02158/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2019.02158/full

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