The "Goldilocks Effect" in Cystic Fibrosis: identification of a lung phenotype in the <it>cftr</it> knockout and heterozygous mouse

<p>Abstract</p> <p>Background</p> <p>Cystic Fibrosis is a pleiotropic disease in humans with primary morbidity and mortality associated with a lung disease phenotype. However, knockout in the mouse of <it>cftr</it>, the gene whose mutant alleles are responsi...

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Bibliographic Details
Main Authors: Bates Jason HT, Lundblad Lennart KA, Craig Cohen J, Levitzky Michael, Larson Janet E
Format: Article
Language:English
Published: BMC 2004-07-01
Series:BMC Genetics
Online Access:http://www.biomedcentral.com/1471-2156/5/21