Mechanism of CK2.3, a Novel Mimetic Peptide of Bone Morphogenetic Protein Receptor Type IA, Mediated Osteogenesis

Mechanism of CK2.3, a Novel Mimetic Peptide of Bone Morphogenetic Protein Receptor Type IA, Mediated Osteogenesis

Background: Osteoporosis is a degenerative skeletal disease with a limited number of treatment options. CK2.3, a novel peptide, may be a potential therapeutic. It induces osteogenesis and bone formation in vitro and in vivo by acting downstream of BMPRIA through releasing CK2 from the receptor. Howe...

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Bibliographic Details
Main Authors: Vrathasha Vrathasha, Hilary Weidner, Anja Nohe
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:International Journal of Molecular Sciences
Subjects:
bone
osteoporosis
osteogenesis
BMP2
CK2
CK2.3
osteogenic signal transduction
western blots
RT-qPCR
Online Access:https://www.mdpi.com/1422-0067/20/10/2500

Internet

https://www.mdpi.com/1422-0067/20/10/2500

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