Muscle Stem Cell Fate Is Controlled by the Cell-Polarity Protein Scrib

Satellite cells are resident skeletal muscle stem cells that supply myonuclei for homeostasis, hypertrophy, and repair in adult muscle. Scrib is one of the major cell-polarity proteins, acting as a potent tumor suppressor in epithelial cells. Here, we show that Scrib also controls satellite-cell-fat...

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Bibliographic Details
Main Authors: Yusuke Ono, Yoshishige Urata, Shinji Goto, Shunsuke Nakagawa, Patrick O. Humbert, Tao-Sheng Li, Peter S. Zammit
Format: Article
Language:English
Published: Elsevier 2015-02-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715000704