Regulatory factors governing adenosine-to-inosine (A-to-I) RNA editing

Adenosine-to-inosine (A-to-I) RNA editing, the most prevalent mode of transcript modification in higher eukaryotes, is catalysed by the adenosine deaminases acting on RNA (ADARs). A-to-I editing imposes an additional layer of gene regulation as it dictates various aspects of RNA metabolism, includin...

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Bibliographic Details
Main Authors: HuiQi Hong, Jaymie Siqi Lin, Leilei Chen
Format: Article
Language:English
Published: Portland Press, Biochemical Society 2015-03-01
Series:Bioscience Reports
Subjects:
Online Access:http://www.bioscirep.org/bsr/035/e182/bsr035e182.htm