Deletion of running-induced hippocampal neurogenesis by irradiation prevents development of an anxious phenotype in mice.

Deletion of running-induced hippocampal neurogenesis by irradiation prevents development of an anxious phenotype in mice.

Recent evidence postulates a role of hippocampal neurogenesis in anxiety behavior. Here we report that elevated levels of neurogenesis elicit increased anxiety in rodents. Mice performing voluntary wheel running displayed both highly elevated levels of neurogenesis and increased anxiety in three dif...

Full description

Bibliographic Details
Main Authors: Johannes Fuss, Nada M B Ben Abdallah, Frank W Hensley, Klaus-Josef Weber, Rainer Hellweg, Peter Gass
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-09-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20862278/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20862278/?tool=EBI

Similar Items