The role of hRev7, the accessory subunit of hPolζ, in translesion synthesis past DNA damage induced by benzo[a]pyrene diol epoxide (BPDE)

<p>Abstract</p> <p>Background</p> <p>DNA polymerase zeta (Polζ) is a specialized DNA polymerase that, unlike classical replicative polymerases, is capable of replicating past DNA lesions, i.e. of performing translesion synthesis (TLS). The catalytic subunit of hPolζ, hR...

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Bibliographic Details
Main Authors: Maher Veronica M, McCormick J Justin, Fletcher Kathryn L, Neal Jessica A
Format: Article
Language:English
Published: BMC 2010-12-01
Series:BMC Cell Biology
Online Access:http://www.biomedcentral.com/1471-2121/11/97