Functional analysis of Ficolin-3 mediated complement activation.

The recognition molecules of the lectin complement pathway are mannose-binding lectin and Ficolin -1, -2 and -3. Recently deficiency of Ficolin-3 was found to be associated with life threatening infections. Thus, we aimed to develop a functional method based on the ELISA platform for evaluating Fico...

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Bibliographic Details
Main Authors: Estrid Hein, Christian Honoré, Mikkel-Ole Skjoedt, Lea Munthe-Fog, Tina Hummelshøj, Peter Garred
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2978102?pdf=render