Fucoidan Suppresses Hypoxia-Induced Lymphangiogenesis and Lymphatic Metastasis in Mouse Hepatocarcinoma

Fucoidan Suppresses Hypoxia-Induced Lymphangiogenesis and Lymphatic Metastasis in Mouse Hepatocarcinoma

Metastasis, the greatest clinical challenge associated with cancer, is closely connected to multiple biological processes, including invasion and adhesion. The hypoxic environment in tumors is an important factor that causes tumor metastasis by activating HIF-1α. Fucoidan, extracted from brown algae...

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Bibliographic Details
Main Authors: Hongming Teng, Yazong Yang, Hengyun Wei, Zundong Liu, Zhichao Liu, Yanhong Ma, Zixiang Gao, Lin Hou, Xiangyang Zou
Format: Article
Language:English
Published: MDPI AG 2015-06-01
Series:Marine Drugs
Subjects:
fucoidan
lymphangiogenesis
hypoxia
HIF-1α
metastasis
Online Access:http://www.mdpi.com/1660-3397/13/6/3514

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http://www.mdpi.com/1660-3397/13/6/3514

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