Discovery and expansion of gene modules by seeking isolated groups in a random graph process.

A central problem in systems biology research is the identification and extension of biological modules-groups of genes or proteins participating in a common cellular process or physical complex. As a result, there is a persistent need for practical, principled methods to infer the modular organizat...

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Bibliographic Details
Main Authors: Jochen Brumm, Elizabeth Conibear, Wyeth W Wasserman, Jennifer Bryan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2559867?pdf=render