Maternal Hyperleptinemia Is Associated with Male Offspring's Altered Vascular Function and Structure in Mice.

Children of mothers with gestational diabetes have greater risk of developing hypertension but little is known about the mechanisms by which this occurs. The objective of this study was to test the hypothesis that high maternal concentrations of leptin during pregnancy, which are present in mothers...

Full description

Bibliographic Details
Main Authors: Kathleen A Pennington, Francisco I Ramirez-Perez, Kelly E Pollock, Omonseigho O Talton, Christopher A Foote, Constantino C Reyes-Aldasoro, Ho-Hsiang Wu, Tieming Ji, Luis A Martinez-Lemus, Laura C Schulz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4871503?pdf=render