Astrocyte heme oxygenase-1 reduces mortality and improves outcome after collagenase-induced intracerebral hemorrhage

Astrocyte heme oxygenase-1 reduces mortality and improves outcome after collagenase-induced intracerebral hemorrhage

Pharmacotherapies that increase CNS expression of heme oxygenase-1 (HO-1) and other antioxidant proteins have improved outcome in experimental models of spontaneous intracerebral hemorrhage (ICH). In order to more specifically investigate the relationship between HO-1 and ICH outcome, mice expressin...

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Bibliographic Details
Main Authors: Jing Chen-Roetling, Pramod Kamalapathy, Yang Cao, Wei Song, Hyman M. Schipper, Raymond F. Regan
Format: Article
Language:English
Published: Elsevier 2017-06-01
Series:Neurobiology of Disease
Subjects:
Glia
Intracerebral hemorrhage
Nrf2
Stroke
Subarachnoid hemorrhage
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996117300566

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http://www.sciencedirect.com/science/article/pii/S0969996117300566

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