Loss of Bardet-Biedl syndrome proteins causes synaptic aberrations in principal neurons.

Loss of Bardet-Biedl syndrome proteins causes synaptic aberrations in principal neurons.

Bardet-Biedl syndrome (BBS), a ciliopathy, is a rare genetic condition characterised by retinal degeneration, obesity, kidney failure, and cognitive impairment. In spite of progress made in our general understanding of BBS aetiology, the molecular and cellular mechanisms underlying cognitive impairm...

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Bibliographic Details
Main Authors: Naila Haq, Christoph Schmidt-Hieber, Fernando J Sialana, Lorenza Ciani, Janosch P Heller, Michelle Stewart, Liz Bentley, Sara Wells, Richard J Rodenburg, Patrick M Nolan, Elizabeth Forsythe, Michael C Wu, Gert Lubec, P Salinas, Michael Häusser, Philip L Beales, Sofia Christou-Savina
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-09-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3000414

Internet

https://doi.org/10.1371/journal.pbio.3000414

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