A combination of Let-7d, Let-7g and Let-7i serves as a stable reference for normalization of serum microRNAs.

Recent studies have indicated that circulating microRNAs (miRNAs) in serum and plasma are stable and can serve as biomarkers of many human diseases. Measurement of circulating miRNAs with sufficient sensitivity and precision, however, faces some special challenges, among which proper normalization i...

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Bibliographic Details
Main Authors: Xi Chen, Hongwei Liang, Danping Guan, Cheng Wang, Xiaoyun Hu, Lin Cui, Sidi Chen, Chunni Zhang, Junfeng Zhang, Ke Zen, Chen-Yu Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3818225?pdf=render