Effects of Antiarrhythmic Drugs on Apoptotic Pathways in H9c2 Cardiac Cells

Abstract.: Antiarrhythmic drugs may induce cellular apoptosis in the heart. By using representatives of 5 different categories of antiarrhythmic drugs, that is, pilsicainide, propranolol, nifekalant, verapamil, and amiodarone, we investigated whether these ion channel blockers or β-antagonists affec...

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Bibliographic Details
Main Authors: Shojiro Isomoto, Kawakami Atsushi, Arakaki Tatsuya, Yamashita Shunichi, Yano Katsusuke, Ono Katsushige
Format: Article
Language:English
Published: Elsevier 2006-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319344366