The Challenging Riddle about the Janus-Type Role of Hsp60 and Related Extracellular Vesicles and miRNAs in Carcinogenesis and the Promises of Its Solution

The Challenging Riddle about the Janus-Type Role of Hsp60 and Related Extracellular Vesicles and miRNAs in Carcinogenesis and the Promises of Its Solution

Hsp60 is one of the most ancient and evolutionarily conserved members of the chaperoning system. It typically resides within mitochondria, in which it contributes to maintaining the organelle’s proteome integrity and homeostasis. In the last few years, it has been shown that Hsp60 also occurs in oth...

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Bibliographic Details
Main Authors: Sabrina David, Alessandra Maria Vitale, Alberto Fucarino, Federica Scalia, Giuseppe Vergilio, Everly Conway de Macario, Alberto J. L. Macario, Celeste Caruso Bavisotto, Alessandro Pitruzzella
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Applied Sciences
Subjects:
Hsp60
chaperonopathies
carcinogenesis
extracellular vesicle (EV)
miRNA
chaperonotherapy
Online Access:https://www.mdpi.com/2076-3417/11/3/1175

Internet

https://www.mdpi.com/2076-3417/11/3/1175

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