Crystallographic models of SARS-CoV-2 3CLpro: in-depth assessment of structure quality and validation

Crystallographic models of SARS-CoV-2 3CLpro: in-depth assessment of structure quality and validation

The appearance at the end of 2019 of the new SARS-CoV-2 coronavirus led to an unprecedented response by the structural biology community, resulting in the rapid determination of many hundreds of structures of proteins encoded by the virus. As part of an effort to analyze and, if necessary, remediate...

Full description

Bibliographic Details
Main Authors: Mariusz Jaskolski, Zbigniew Dauter, Ivan G. Shabalin, Miroslaw Gilski, Dariusz Brzezinski, Marcin Kowiel, Bernhard Rupp, Alexander Wlodawer
Format: Article
Language:English
Published: International Union of Crystallography 2021-03-01
Series:IUCrJ
Subjects:
covid-19
sars-cov-2
coronavirus
structure-guided drug discovery
ligand validation
viral proteases
protein data bank
reproducibility
Online Access:http://scripts.iucr.org/cgi-bin/paper?S2052252521001159

Internet

http://scripts.iucr.org/cgi-bin/paper?S2052252521001159

Similar Items