The role of <it>CACNA1S </it>in predisposition to malignant hyperthermia

<p>Abstract</p> <p>Background</p> <p>Malignant hyperthermia (MH) is an inherited pharmacogenetic disorder of skeletal muscle, characterised by an elevated calcium release from the skeletal muscle sarcoplasmic reticulum. The dihydropyridine receptor (DHPR) plays an essen...

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Bibliographic Details
Main Authors: Halsall P Jane, Robinson Rachel L, Morris Andrew, Leo Vincenzo, Ringrose Christopher, Carpenter Danielle, Hopkins Philip M, Shaw Marie-Anne
Format: Article
Language:English
Published: BMC 2009-10-01
Series:BMC Medical Genetics
Online Access:http://www.biomedcentral.com/1471-2350/10/104