Different aspects of Alzheimer’s disease-related amyloid β-peptide pathology and their relationship to amyloid positron emission tomography imaging and dementia

Different aspects of Alzheimer’s disease-related amyloid β-peptide pathology and their relationship to amyloid positron emission tomography imaging and dementia

Abstract Alzheimer’s disease (AD)-related amyloid β-peptide (Aβ) pathology in the form of amyloid plaques and cerebral amyloid angiopathy (CAA) spreads in its topographical distribution, increases in quantity, and undergoes qualitative changes in its composition of modified Aβ species throughout the...

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Main Authors: Dietmar Rudolf Thal, Alicja Ronisz, Thomas Tousseyn, Ajeet Rijal Upadhaya, Karthikeyan Balakrishnan, Rik Vandenberghe, Mathieu Vandenbulcke, Christine A. F. von Arnim, Markus Otto, Thomas G. Beach, Johan Lilja, Kerstin Heurling, Aruna Chakrabarty, Azzam Ismail, Christopher Buckley, Adrian P. L. Smith, Sathish Kumar, Gill Farrar, Jochen Walter
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Acta Neuropathologica Communications
Subjects:
Alzheimer’s disease
Amyloid β peptide
Staging
Amyloid load
Soluble amyloid
Insoluble amyloid
Online Access:http://link.springer.com/article/10.1186/s40478-019-0837-9

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http://link.springer.com/article/10.1186/s40478-019-0837-9

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