Ultrafine carbon particles down-regulate CYP1B1 expression in human monocytes

<p>Abstract</p> <p>Background</p> <p><it>Cytochrome P450 monoxygenases </it>play an important role in the defence against inhaled toxic compounds and in metabolizing a wide range of xenobiotics and environmental contaminants. In ambient aerosol the ultrafine...

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Bibliographic Details
Main Authors: Ziegler-Heitbrock Loems, Seidel Albrecht, Schramm Karl-Werner, Stanzel Franz, Frankenberger Marion, Eder Christiane, Hofer Thomas PJ
Format: Article
Language:English
Published: BMC 2009-10-01
Series:Particle and Fibre Toxicology
Online Access:http://www.particleandfibretoxicology.com/content/6/1/27