Alternatively spliced tissue factor is not sufficient for embryonic development.

Alternatively spliced tissue factor is not sufficient for embryonic development.

Tissue factor (TF) triggers blood coagulation and is translated from two mRNA splice isoforms, encoding membrane-anchored full-length TF (flTF) and soluble alternatively-spliced TF (asTF). The complete knockout of TF in mice causes embryonic lethality associated with failure of the yolk sac vasculat...

Full description

Bibliographic Details
Main Authors: Susanna H M Sluka, Alexander Akhmedov, Johannes Vogel, Dusten Unruh, Vladimir Y Bogdanov, Giovanni G Camici, Thomas F Lüscher, Wolfram Ruf, Felix C Tanner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4039448?pdf=render

Internet

http://europepmc.org/articles/PMC4039448?pdf=render

Similar Items