Potential combination topical therapy of anal fissure: development, evaluation, and clinical study†

To treat anal fissure, internal anal sphincterotomy may be associated with surgical risks and incidence of incontinence. Botulinum toxin injection into the anal sphincter is invasive and expensive. Headache and hypotension hindered topical treatment with glyceryl trinitrate. Greater patient complian...

Full description

Bibliographic Details
Main Authors: Amgad E. Salem, Elham A. Mohamed, Hosam M. Elghadban, Galal M. Abdelghani
Format: Article
Language:English
Published: Taylor & Francis Group 2018-01-01
Series:Drug Delivery
Subjects:
Online Access:http://dx.doi.org/10.1080/10717544.2018.1507059