Molecular genomic features associated with in vitro response of the NCI‐60 cancer cell line panel to natural products

Molecular genomic features associated with in vitro response of the NCI‐60 cancer cell line panel to natural products

Natural products remain a significant source of anticancer chemotherapeutics. The search for targeted drugs for cancer treatment includes consideration of natural products, which may provide new opportunities for antitumor cytotoxicity as single agents or in combination therapy. We examined the asso...

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Bibliographic Details
Main Authors: Julia Krushkal, Simarjeet Negi, Laura M. Yee, Jason R. Evans, Tanja Grkovic, Alida Palmisano, Jianwen Fang, Hari Sankaran, Lisa M. McShane, Yingdong Zhao, Barry R. O'Keefe
Format: Article
Language:English
Published: Wiley 2021-02-01
Series:Molecular Oncology
Subjects:
cancer cell lines
DNA mutation
drug response
gene expression
natural products
single nucleotide variation
Online Access:https://doi.org/10.1002/1878-0261.12849

Internet

https://doi.org/10.1002/1878-0261.12849

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