miR-135b Promotes Cancer Progression by Targeting Transforming Growth Factor Beta Receptor II (TGFBR2) in Colorectal Cancer.

miR-135b Promotes Cancer Progression by Targeting Transforming Growth Factor Beta Receptor II (TGFBR2) in Colorectal Cancer.

The transforming growth factor beta (TGF-β) signaling pathway is a tumor-suppressor pathway that is commonly inactivated in colorectal cancer (CRC). The inactivation of TGFBR2 is the most common genetic event affecting the TGF-β signaling pathway. However, the mechanism by which cancer cells downreg...

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Bibliographic Details
Main Authors: Jialu Li, Hongwei Liang, Ming Bai, Tao Ning, Cheng Wang, Qian Fan, Yanbo Wang, Zheng Fu, Nan Wang, Rui Liu, Ke Zen, Chen-Yu Zhang, Xi Chen, Yi Ba
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4462589?pdf=render

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http://europepmc.org/articles/PMC4462589?pdf=render

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