Activated macrophages control human adipocyte mitochondrial bioenergetics via secreted factors

Activated macrophages control human adipocyte mitochondrial bioenergetics via secreted factors

Objective: Obesity-associated WAT inflammation is characterized by the accumulation and local activation of macrophages (MΦs), and recent data from mouse studies suggest that macrophages are modifiers of adipocyte energy metabolism and mitochondrial function. As mitochondrial dysfunction has been as...

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Bibliographic Details
Main Authors: Michaela Keuper, Stephan Sachs, Ellen Walheim, Lucia Berti, Bernhard Raedle, Daniel Tews, Pamela Fischer-Posovszky, Martin Wabitsch, Martin Hrabě de Angelis, Gabi Kastenmüller, Matthias H. Tschöp, Martin Jastroch, Harald Staiger, Susanna M. Hofmann
Format: Article
Language:English
Published: Elsevier 2017-10-01
Series:Molecular Metabolism
Subjects:
Cytokines
Oxidative phosphorylation
Glycolysis
Cellular metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877817304477

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http://www.sciencedirect.com/science/article/pii/S2212877817304477

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