Immune gene expression profiling reveals heterogeneity in luminal breast tumors

Immune gene expression profiling reveals heterogeneity in luminal breast tumors

Abstract Background Heterogeneity of immune gene expression patterns of luminal breast cancer (BC), which is clinically heterogeneous and overall considered as low immunogenic, has not been well studied especially in non-European populations. Here, we aimed at characterizing the immune gene expressi...

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Bibliographic Details
Main Authors: Bin Zhu, Lap Ah Tse, Difei Wang, Hela Koka, Tongwu Zhang, Mustapha Abubakar, Priscilla Lee, Feng Wang, Cherry Wu, Koon Ho Tsang, Wing-cheong Chan, Sze Hong Law, Mengjie Li, Wentao Li, Suyang Wu, Zhiguang Liu, Bixia Huang, Han Zhang, Eric Tang, Zhengyan Kan, Soohyeon Lee, Yeon Hee Park, Seok Jin Nam, Mingyi Wang, Xuezheng Sun, Kristine Jones, Amy Hutchinson, Belynda Hicks, Ludmila Prokunina-Olsson, Jianxin Shi, Montserrat Garcia-Closas, Stephen Chanock, Xiaohong R. Yang
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Breast Cancer Research
Subjects:
Tumor-infiltrating lymphocytes
Immune subtypes
Luminal breast cancer
Asian
Somatic mutations
APOBEC3B germline deletion
Online Access:https://doi.org/10.1186/s13058-019-1218-9

Internet

https://doi.org/10.1186/s13058-019-1218-9

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