Indomethacin Decreases Arachidonic Acid Uptake in HCA-7 Human Colon Cancer Cells

Nonsteroidal anti-inflammatory drugs (NSAIDs) reduce the incidence of colorectal cancer. However, evidence is accumulating that NSAIDs have anti-cancer effects in addition to inhibiting cyclooxygenase (COX)-mediated prostanoid biosynthesis. We now show that indomethacin, a popular NSAID, significant...

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Bibliographic Details
Main Authors: Takashi Orido, Hiromichi Fujino, Yuta Hasegawa, Kaori Toyomura, Tatsuo Kawashima, Toshihiko Murayama
Format: Article
Language:English
Published: Elsevier 2008-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319313489