The Role of IL-22 in Viral Infections: Paradigms and Paradoxes

Interleukin-22 (IL-22) is a member of the IL-10 family of cytokines. Hematopoietic cells express IL-22, and this cytokine signals through the heterodimeric IL-22R expressed by non-hematopoietic cells. A growing body of evidence points towards a role for IL-22 in a diverse array of biological functio...

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Bibliographic Details
Main Authors: Silvia eGimeno Brias, Gabrielle eStack, Maria A Stacey, Alec J Redwood, Ian R Humphreys
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-05-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00211/full