Is insulin-like growth factor-1 involved in Parkinson’s disease development?

Is insulin-like growth factor-1 involved in Parkinson’s disease development?

Abstract Parkinson’s disease (PD) is a neurodegenerative disorder that results in the death of dopaminergic neurons within the substantia nigra pars compacta and the reduction in dopaminergic control over striatal output neurons, leading to a movement disorder most commonly characterized by akinesia...

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Bibliographic Details
Main Authors: Inma Castilla-Cortázar, Gabriel A. Aguirre, Giovana Femat-Roldán, Irene Martín-Estal, Luis Espinosa
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Journal of Translational Medicine
Subjects:
Parkinson’s disease
IGF-1
Aging
Dopamine
Estrogens
Central nervous system
Online Access:https://doi.org/10.1186/s12967-020-02223-0

Internet

https://doi.org/10.1186/s12967-020-02223-0

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