The marker of alkyl DNA base damage, N7-methylguanine, is associated with semen quality in men

Abstract Sperm DNA contains a range of DNA base damage that can arise, in part, from exposure to methylating agents. However, the effects are not fully characterized and so the aim of this study was to investigate associations between semen quality and the levels of N7-methyldeoxyguanosine (N7-MedG)...

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Bibliographic Details
Main Authors: B. Altakroni, C. Nevin, M. Carroll, C. Murgatroyd, G. Horne, D. R. Brison, A. C. Povey
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-81674-x