Aspirin exerts anti-tumor effect through inhibiting Blimp1 and activating ATF4/CHOP pathway in multiple myeloma

Aspirin exerts anti-tumor effect through inhibiting Blimp1 and activating ATF4/CHOP pathway in multiple myeloma

B lymphocyte-induced maturation protein-1 (Blimp1) is a key regulator that promotes the terminal differentiation of mature B lymphocytes into plasma cells, and is essential for the survival of Multiple myeloma (MM)cells. However, the expression of Blimp1 in MM and its effect on the signaling pathway...

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Bibliographic Details
Main Authors: Hongchun Liu, Chao Xiong, Junwen Liu, Ting Sun, Zhenzhen Ren, Yuqing Li, Jie Geng, Xuebing Li
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Aspirin
Multiple myeloma
Blimp1
ATF4
CHOP
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332220301967

Internet

http://www.sciencedirect.com/science/article/pii/S0753332220301967

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