SESTRINs: Emerging Dynamic Stress-Sensors in Metabolic and Environmental Health

SESTRINs: Emerging Dynamic Stress-Sensors in Metabolic and Environmental Health

Proper timely management of various external and internal stresses is critical for metabolic and redox homeostasis in mammals. In particular, dysregulation of mechanistic target of rapamycin complex (mTORC) triggered from metabolic stress and accumulation of reactive oxygen species (ROS) generated f...

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Bibliographic Details
Main Authors: Seung-Hyun Ro, Julianne Fay, Cesar I. Cyuzuzo, Yura Jang, Naeun Lee, Hyun-Seob Song, Edward N. Harris
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Sestrins
environmental stress
aging
metabolic disease
obesity/inflammation
mTORC
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2020.603421/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2020.603421/full

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