Urinary Excretion of Iohexol as a Permeability Marker in a Mouse Model of Intestinal Inflammation: Time Course, Performance and Welfare Considerations

Urinary Excretion of Iohexol as a Permeability Marker in a Mouse Model of Intestinal Inflammation: Time Course, Performance and Welfare Considerations

Intestinal permeability (IP) tests are used to assess intestinal damage in patients and research models. The probe iohexol has shown advantages compared to <sup>51</sup>Cr-EDTA or absorbable/nonabsorbable sugars. During IP tests, animals are housed in metabolic cages (MCs) to collect uri...

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Bibliographic Details
Main Authors: Victoria Ortín-Piqueras, Tobias L Freitag, Leif C Andersson, Sanna H Lehtonen, Seppo K Meri, Thomas Spillmann, Rafael Frias
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Animals
Subjects:
duodenitis
inflammation
intestinal permeability
iohexol
metabolic cage
mouse
Online Access:https://www.mdpi.com/2076-2615/11/1/79

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https://www.mdpi.com/2076-2615/11/1/79

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