Substance P Antagonist Aprepitant Shows no Additive Effect Compared with Standardized Topical Treatment Alone in Patients with Atopic Dermatitis

Substance P Antagonist Aprepitant Shows no Additive Effect Compared with Standardized Topical Treatment Alone in Patients with Atopic Dermatitis

Atopic dermatitis (AD) is a chronic, itchy, inflammatory skin disorder that may worsen due to stress and anxiety. Tachykinins have been suggested to be involved in the inflammation in AD, as well as pruritus. Aprepitant is a NK-1 receptor antagonist. This open randomized trial evaluated the effect o...

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Bibliographic Details
Main Authors: Louise Lönndahl, Mikael Holst, Maria Bradley, Hassan Killasli, Johan Heilborn, Martin A. Hall, Elvar Theodorsson, Jadwiga Holmberg, Klas Nordlind
Format: Article
Language:English
Published: Society for Publication of Acta Dermato-Venereologica 2017-12-01
Series:Acta Dermato-Venereologica
Subjects:
anxiety
atopicdermatitis
aprepitant
depression
neurokinin1receptor
pruritus
SCORAD
substanceP
Online Access: https://www.medicaljournals.se/acta/content/html/10.2340/00015555-2852

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https://www.medicaljournals.se/acta/content/html/10.2340/00015555-2852

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